Curriculum Vitae

Etudes et diplômes universitaires

1) Doctorat en Médecine 1983-1990 ULB

ULB Université Libre de Bruxelles (ULB)

4ème doctorat : 89-90 : 1ère session : grande distinction

2) Spécialisation en Médecine Interne 1990-1996 ULB

CHU Brugmann et Hôpital Erasme`

3) Spécialisation en Néphrologie et transplantation rénale 1994-1997 ULB

CHU Brugmann et Hôpital Erasme

4) DEA Erasme 2003 ULB

5) Diplômes interuniversitaires

Université Paris-Descartes (U. Paris D.) - Paris 5

a) Infection et transplantation 2007-2008 U. Paris D.

b) Rein et Maladies systémiques 2010-2011 U. Paris D.

6) Thèse de Doctorat en transplantation rénale 2015 ULB

- Etude des réponses humorales en transplantation rénale

- Thèse annexe :

Les nouvelles générations d’inhibiteurs du mTOR en transplantation rénale:

pour une diminution du risque cancéreux ?

Occupation professionnelles : Néphrologue

1) Résident en Néphrologie :

CHU Brugmann 01.10.96 - 30.09.1998
Hôpital Erasme 01.10 98 - 01.01.2004

2) Chef de Clinique Adjoint en Néphrologie et Transplantation rénale

Hôpital Erasme depuis 2004 -

3) Néphrologue : consultations

Hôpital Erasme - ULB
- mardi et mercredi
Polyclinique de Nivelle - ULB depuis le 01.01.2019 -
- jeudi après-midi
Centre Médical de L'Alliance à Braine-L'Alleud depuis le 01.01.2019 -
- jeudi matin

Publications

1. Surélévation des mesures de glycémie par lecteur chez des patients en DPCA traités par Icodextrine.

Wens R, Devriendt J, Collart F, Broeders N, Mestrez F, Dratwa M.

Bulletin de Dialyse Péritonéale (BDP). 1997 ; 7(3) : 61-7.

2. Mycophenolate Mofetil, together with Cyclosporine A, prevents anti-OKT3 antibody response in kidney transplant recipients.

Broeders N, Wissing M, Crusiaux A, Kinnaert P, Vereerstraeten P, Abramowicz D.

Journal of the American Society of Nephrology. 1989 : 1521-5.

3. Actualité thérapeutique : Le Mycophénolate Mofetil.

Abramowicz D, Broeders N, Wissing M, Sternon J.

Revue Médicale de Bruxelles. 1998 ; 3 : 139-43.

4. A previously undescribed side effect of Icodextrin : overestimation of glycemia by glucose analyser.

Wens R, Taminne M, Devriendt J, Collart F, Broeders N, Mestrez F, Germanos H, Dratwa M.

Peritoneal Dialysis International. 1998 ; 18 : 603-9.

5. Fibrate-induced renal dysfunction: is Gemfibrozil the only non-nephrotoxic agent?

Broeders N, Knoop C, Antoine M, Abramowicz D.

Transplantation. 1999 ; 67 : S170.

6. Induction with anti-CD3 antibodies.

Abramowicz D, Wissing M, Broeders N.

Current Opinion in Organ Transplantation. 1999 ; 4 : 312-7.

7. Letter to the editor for the article « Drug treatment of lipid disorders » by R.H.Knopp. N. N Engl.J.Med.1999; 341:498-511.

Broeders N, Knoop C, Abramowicz D.

N Engl J Med. 1999 ; 341 (26) : 2020-1.

8. Nephrotoxicity of calcineurin inhibitors: new therapeutic approaches.

Abramowicz D, Wissing M, Broeders N.

Transplantation Proceedings. 2000; 32 (S1A), 3S-5S.

9. Stratégies d’immunosuppression en transplantation rénale au début du 3ème millénaire

Abramowicz D, Wissing M, Broeders N.

Actualités néphrologiques de l’Hopital Necker. 2000 ; 99-113.

10. Hypercholesterolemia is associated with increased kidney graft loss due to chronic rejection in male patients with previous acute rejection.

Wissing KM, Abramowicz D, Broeders N, Vereerstraeten P.

Transplantation. 2000; 70 (3) : 464-72.

11. Fibrate-induced increase in blood urea and creatinine: is gemfibrozil the only innocuous agent?

Broeders N, Knoop C, Antoine M, Tielemans C, Abramowicz D.

Nephrol Dial Transplant. 2000 ; 15 : 1993-9.

12. Traitement immunosuppresseur en transplantation rénale.

Broeders N, Wissing M, Abramowicz D.

Encyclopédie Médico-chirurgicale, 18-065-F-10, 2001 ; Editions Scientifiques et Médicales Elsevier SAS, Paris, France.

13. Peroxisome proliferator-activated receptors (PPARs): novel therapeutic targets in renal disease.

Broeders N, Abramowicz D.

Kidney international. 2002 ; 61(1) : 354-5.

14. The medico-surgical department of nephrology dialysis and renal transplantation.

Vanherweghem JL, Abramowicz D, Broeders N, De Pauw L, Le Moine A, Nortier J, Tielemans C. Wissing M.

Revue médicale de Bruxelles. 2002 ; 23(S2) : 115-22.

15. Immunosuppression for renal transplantation.

Abramowicz D, Wissing M, Broeders N.

Oxford Textbook of Clinical Nephrology, 3rdedition (Davison et al. Eds),

Oxford University Press. Oxford, UK.2004

16. A novel mutation of Tumor Necrosis Factor Receptor alpha type 1 associated with TRAPS and amyloidosis

Broeders N, Abramowicz D, Abramowicz M, Parma J.

Am J Med Genet. 2004 ; 128A (3) : 331.

17. A controlled study of vitamin D3 to prevent bone loss in renal-transplant patients receiving low doses of steroids.

Wissing M, Broeders N, Moreno-Reyes R, Gervy C, Stallenberg B, Abramowicz D.

Transplantation. 2005 ; 79(1) : 108-15.

18. Conversion from tacrolimus to cyclosporin is associated with a significant improvement of glucose metabolism in patients with new-onset diabetes mellitus after renal transplantation

Ben Bouchta NB, Ghisdal L, Abramowicz D, Broeders N, Surquin M, Hoang AD, Martin Wissing K.

Transplant Proc. 2005 ; 37(4) : 1857-60.

19. Effect of atorvastatin therapy and conversion to tacrolimus on hypercholesterolemia and endothelial dysfunction after renal transplantation.

Wissing KM, Unger P, Ghisdal L, Broeders N, Berkenboom G, Carpentier Y, Abramowicz D.

Transplantation. 2006 ; 82(6) : 771-8.

20. Impact des imunosuppresseurs sur les réponses vaccinales

Broeders N, Abramowicz D.

Le Courier de la Transplantation. 2007 ; 7(3) : 127-9.

21. Evolution of immunoglobulin and mannose binding protein levels after renal transplantation: association with infectious complications.

Broeders N, Wissing KM, Hazzan M, Ghisdal L, Hoang AD, Noel C, Mascart F, Abramowicz D.

Transplant International. 2008. 21(1) : 57–64.

22. HLA Mismatches Remain Risk Factors for Acute Kidney Allograft Rejection in Patients Receiving Quadruple Immunosuppression With Anti-Interleukin-2 Receptor Antibodies.

Wissing KM, Fomegne G, Broeders N, Ghisdal L, Hoang AD, Mikhalski D, Donckier V, Vereerstraeten P, Abramowicz D.

Transplantation 2008 ; 85 (3) : 411-6.

23. Cold ischemia is a major determinant of acute rejection and renal graft survival in the modern era of immunosuppression.

Dimitri M, Wissing KM, Ghisdal L, Broeders N, Touly M, Hoang AD, Loi P, Mboti F, Donckier V, Vereerstraeten P, Abramowicz D .

Transplantation. 2008 ; 85(7S) : S3-9.

24. Conversion from tacrolimus to cyclosporine A for new-onset diabetes after transplantation:a single- centre experience in renal transplanted patients and review of the literature.

Ghisdal L, Ben Bouchta N, Broeders N, Crenier L, Hoang AD, Abramowicz D, Wissing KM

Transplant international. 2008 ; 21(2) : 146-51.

25. Experience about more than 2000 renal transplantations at the university of Brussels.

Madhoun P, Wissing M, Broeders N, Ghisdal L, Hoang A, Loi P, Michalsky D, Bollens R, Donckier V, Hooghe L, Janssen F, Hall M, Depierreux M, Kinnaert P, Vereerstraeten P, Abramowicz D

Revue médicale de Bruxelles. 2008 ; 29(1 Suppl) : S 33-9.

26. Conversion to sirolimus for chronic renal allograft dysfunction: risk factors for graft loss and severe side effects.

Abramowicz D, Hadaya K, Hazzan M, Broeders N, Hoang A, Ghisdal L, Noel C, Wissing KM.

Nephrology, dialysis, transplantation. Official publication of the European Dialysis and Transplant Association - European Renal Association. 2008 ; 23(11) : 3727-9.

27. Thrombophilic factors do not predict outcomes in renal transplant recipients under prophylactic acetylsalicylic acid.

Ghisdal L, Broeders N, Wissing KM, Saidi A, Bensalem T, Mbaba Mena J, Lemy A, Wijns W, Pradier O, Hoang AD, Mikhalski D, Donckier V, Cochaux P, El Housni H, Abramowicz M, Vereerstraeten P, Abramowicz D.

Am J Transplant. 2010 ; 10(1): 99-105.

28. Twenty-five years of calcineurin inhibitors use in kidney transplantation at Erasme Hospital.

Vereerstraeten P, Wissing M, Broeders N, Hoang AD, Mikhalski D, Donckier V, Abramowicz D.

Rev Med Brux. 2010 ; 31(2) : 93-101.

29. Major histocompatibility complex class1 chain-related antigen and antibodies: sensitizing events and impact on renal graft outcomes.

Lemy A, Andrien M, Wissing KM, Ryhahi K, Vandersarren A, Racapé J, Heylen C, Ghisdal L, Broeders E, Vereerstraeten P, Toungouz M, Abramowicz D.

Transplantation. 2010 ; 90(2) : 168-74.

30. Ineligibility for renal transplantation: prevalence, causes and survival in a consecutive cohort of 445 patients.

Kianda MN, WissingKM, Broeders EN, Lemy A, Ghisdal L, Hoang AD, Mikhalski D, Donckier V, Vereerstraeten P, Abramowicz,D.

Clin Transplant2011 ; 25(4) : 576-83.

31. Conversion from PrografÒto AdvagrafÒamong kidney transplant recipients results in sustained decrease in tacrolimus exposure.

JM Hougardy JM, N Broeders N, Kianda M, Massart A, Madhoun P, Le Moine A, Hoang AD, Mikhalski D, Wissing KM, Abramowicz D.

Transplantation 2011 ; 91(5) : 566-9.

32. Recurrent leishmaniasis in kidney transplant recipients: report of 2 cases and systematic review of the literature.

Simon I, Wissing KM, Del Marmol V, Antinori S, Remmelink M, Broeders EN, Nortier JL, Corbellino M, Abramowicz D, Cascio A.

Transplant Infectious Disease. 2011 ; 13(4) : 397-406.

33. Thrombophilic factors in Stage V chronic kidney disease patients are largely corrected by renal transplantation.

Ghisdal L, Broeders N, Wissing KM, Mena JM, Lemy A, Wijns W, Pradier O, Donckier V, Racapé J, Vereerstraeten P, Abramowicz D.

Nephrol Dial Transplant. 2011 ; 26(8) : 2700-5.

34. Influenza A/H1N1 Vaccine in Patients Treated by Kidney Transplant or Dialysis: a Cohort Study.

Broeders EN, Hombrouck A, Lemy A, Wissing K M, Racape J, Gastaldello K, Massart A, Van Gucht S, Weichselbaum L, De Mul A, Brochier B, Thomas I, Abramowicz D.

Clin J Am Soc Nephrol. 2011 ; 6(11) : 2573-8.

35. Combined introduction of anti-IL2 receptor antibodies, mycophenolic acid and tacrolimus effect on malignancies after renal transplantation in a single centre retrospective cohort study.

Braconnier P, Delmarmol V, Broeders N, Kianda M, Massart A, Lemy A, Ghisdal L, Le Moine A, Madhoun P, Racapé J, Abramowicz D, Wissing KM.

Nephrol Dial Transplant. 2012 ; 27(6) : 2547-53.

36. Shipping donor kidneys within Eurotransplant: outcomes after renal transplantation in a single- centre cohort study.

Wissing KM, Broeders N, Massart A, Kianda M, Ghisdal L, Lemy A, Hoang AD, Mikhalski D, Donckier V, Racapé J, Vereerstraeten P, de Boer J, Abramowicz D.

Nephrol Dial Transplant.2012 ; 27(9) : 3638-44.

37. Sirolimus and secondary skin-cancer prevention in kidney transplantation.

Euvrard S, Morelon E, Rostaing L, Goffin E, Brocard A, Tromme I, Broeders N, del Marmol V, Chatelet V, Dompmartin A, Kessler M, Serra AL, Hofbauer GFL, Pouteil-Noble CL, Campistol JM, Kanitakis J, Roux, AS, Decullier E, Dantal J, for the TUMORAPA Study Group.

N Engl J Med. 2012 ; 367 : 329-39.

38. Does Loss to Follow-Up Affects Outcomes of Renal Transplantation? A Retrospective Study of 849 Patients.

Kianda MN, Wissing MK, Maddhoun P, Hougardy J-M, Broeders N, Benhamed A, Massart A, Vereerstraeten P, Hoang A-D, Racape J, Abramowicz D.

Transplantation 11/2012; 94(10S):845.

39. Large decrease of anti-tetanus anatoxin and anti-pneumococcal antibodies at one year after renal transplantation.

Broeders EN, Wissing KM, Ghisdal L, Lemy A, Hoang AD, Vereerstraeten P, Mascart F, Abramowicz D

Clin Nephrol. 2013 ; 79(4) : 313-7.

40. Complement Factor H functional assay may help to monitor atypical haemolytic uraemic syndrome: a pilot study.

Massart A, Golmarvi S, Hachimi-Idrissi S, Broeders E, Tournay Y, Nortier J, Abramowicz D. Tielemans C, Stordeur P.

Acta Clin Belg. 2013 ; 68(1): 9-14.

41. Ticlopidine and clopidogrel, sometimes combined with aspirin, only minimally increase the surgical risk in renal transplantation: a case-control study.

Benahmed A, Kianda M, Ghisdal L, Broeders N, Massart A, Lemy A, Mikhalski D, Hoang AD, Donckier V, Sadis C, Le Moine A, Madhoun P, Racape J, Wissing M, Abramowicz D.

Nephrol Dial Transplant. 2014 ; 29 : 463-6.

42. Does Basiliximab induction trigger life-threatening ARDS and shock in young patients.

Massart A, Heenen S, Bejjani G, Hoang AD, Mikhalski D, Broeders E, Creteur J, De Backer D, Abramowicz D.

Clin Nephrol. 2015 ; 83(1) : 61-70.

43. Patient and graft outcome in current era of immunosuppression: A single center pilot study.

Goubella A, Broeders N, Racapé J, Hamade A, Massart A, Hougardy JM, Hoang AD, Mikhalski D, Baudoux T, Gankam F, Madhoun P, Janssen F, Le Moine A, Nortier J, Vereerstraeten P.

Acta Clin Belg. February. 2015 ; 70(1) : 23-9.

44. A “silent”, new polymorphism of factor h and apparent de novo atypical hemolytic uraemic syndrome after kidney transplantation.

Broeders EN, Stordeur P, Rorive S, Dahan K.

BMJ Case Rep 2014. Dec 23. doi:10.1136/ bcr-2014-207630.

45. Bacillus Calmette-Guerin therapy in non-muscle-invasive bladder carcinoma after renal transplantation for end-stage aristolochic acid nephropathy.

Broeders N, Roumeguère T, Jayaswal A, Rorive S, Quackels T, Pozdzik A, Arlt VM, Shmeiser HH, Nortier J.

Transplant International. 2015 ; 28: 199-205.

46. A New HLA Allocation Procedure of Kidneys From Deceased Donors in the Current Era of Immunosuppression.

Broeders N, Racape J, Hamade A, Massart A, Hoang AD, Mikhalski D, Le Moine A, Vereerstraeten P.

Transplantation Proceedings. 2015 ; 47: 267-274

47. Anti-PLA2R and anti-NEP antibodies in membranous nephropathy : an update.

Pozdzik A, Debiec H, Brochériou I, Husson C, Rorive S, Broeders N, Le Moine A, Ronco P ,Nortier.

Rev Med Brux. 2015 ; 36 : 171-176.

48. Encapsulating peritoneal sclerosis in a kidney graft recipient unmasked by everolimus switch.

Pozdzik A, Fernandez V, Demetter P, Tooulou M, Matos C, Gammar N, Broeders N, Dratwa M, Nortier

Perit Dial Int 2015 Dec;35(7):769-71

49. Delayed Graft Function in Kidney Transplants: Time Evolution, Role of Acute Rejection, Risk Factors, and Impact on Patient and Graft Outcome.

Chaumont, M, Racapé J, Broeders N, El Mountahi F, Massart A, Baudoux T, Hougardy J-M, Mikhalski D, Hamade A, Le Moine A, Abramowicz D, Vereerstraeten P. Journal of Transplantation 2015, Article ID 163757, 9. http://dx.doi.org/10.1155/2015/163757

50. High-urgency kidney transplantation in the Eurotransplant Kidney Allocation System: success or waste of organs?

The Eurotransplant 15-year all-centre survey. Volker Assfalg, Norbert Hüser,Marieka van Meel, Bernhard Haller, Axel Rahmel,Jan de Boer,Edouard Matevossian, Alexander Novotny, Noel Knops,Laurent Weekers, Helmut Friess,Johann Pratschke, Reinhold Függer, Otmar Janko,Susanne Rasoul-Rockenschaub, Jean-Louis Bosmans, Nilufer Broeders, Patrick Peeters, Michel Mourad,Dirk Kuypers,Jasna Slaviček,Anjy Muehlfeldt, Florian Sommer, Richard Viebahn, Andreas Pascher, Markus van der Giet, Frans Zantvoort, Rainer P. Woitas, Juliane Putz,Klaus Grabitz, Andreas Kribben, Ingeborg Hauser, Przemyslaw Pisarski, Rolf Weimer,Thomas H. Lorf, Paola Fornara,Christian H. Morath, Björn Nashan,Frank Lehner,Volker Kliem,Urban Sester,Marc-Oliver Grimm, Thorsten Feldkamp, Robert Kleinert, Wolfgang Arns,Christian H. Mönch, Markus Bo Schoenberg, Martin Nitschke, Bernd Krüger,Stefan Thorban, Helmut P. Arbogast, Heiner H. Wolters, Tanjy Maier,Jens Lutz,Katharina Heller, Bernhard Banas, Oliver Hakenberg, Martin Kalus,Silvio Nadalin, Frieder Keller, Kai Lopau,Frederike José Bemelman, Shaikh Nurmohamed, Jan-Stephan Sanders, Johan W. de Fijter, Maarten Christiaans, Luuk Hilbrands, Michiel Betjes, Arjan van Zuilenand Uwe Heemann.

Nephrol. Dial. Transplant. (2016). doi: 10.1093/ndt/gfv446. First published online: February 4, 2016.

51. Therapeutic drug monitoring of enteric-coated mycophenolate sodium by limited sampling strategies is associated with a high rate of failure.

Hougardy JM, Maufort L, Cotton F, Coussement J, Mikhalski D, Wissing KM, Le Moine A, Broeders N, Abramowicz D.

Clinical Kidney Journal, 2016, vol. 9, no. 2, 319–323.

52. Genome‐Wide Association Study of Acute Renal Graft Rejection.

Ghisdal L, Baron C, Lebranchu Y, Viklicky O, Konarikova A, Naesens M, Kuypers D, Dinic M, Alamartine E, Touchard Guy, Moussiaux A, Essig M, Rerolle J, Merville P, Taupin J L, Le Meur, Y, Grall-Jezequel A, Glowacki F, Noel C, Legendre C, Anglicheau D, Broeders E N, Coppieters,W, Docampo E, Georges M, Ajarchouh Z, Massart A, Racapé J, Abramowicz D, Abrawowicz M. American Journal of Transplantation 2016; XX: 1–9doi: 10.1111/ajt.13912.

53. Preemptive reduction of immunosuppression upon high urinary polyomavirus loads improves patient survival without affecting kidney graft function.

Broeders E.N, Hamade A, El Mountahi F, Racapé J, Hougardy JM, Le Moine A, Vereerstraeten P. Transpl Infect Dis. 2016 ; 18 : 872-880. doi:10.1111/tid.12603.

54. Severe myoglobinuric acute kidney injury in a kidney recipient: Rapid recovery after hemodialysis with the super high-flux membrane Theralite®.

Goubella A, Gankam Kengne F, Baudoux T, Fagnoul D, Husson C, Ghisdal L, Broeders E.N, Nortier J.

Clinical nephrology. 2017 ; 88(6). DOI: 10.5414/CN109020

55. Donor Cancer Transmission In Kidney Transplantation.

Baudoux T, Gastaldello K, Rorive S, Hamade A, Broeders N, Nortier J.

Kidney Int Rep 2017 Mar 29;2(2):134-137. Epub 2016 Sep 29.

56. Prospective randomized study of conversion from tacrolimus to cyclosporine A to improve glucose metabolism in patients with posttransplant diabetes mellitus after renal transplantation.

Wissing KM, Abramowicz D, Weeckers L, Budde K, Rath T, Broeders N, Kianda M, Kuypers DRJ.

American Journal of Transplantation 2018, 18 (7): 1726-1734.

57. Intoxications aux aristoloches dans le monde : le point en 2018.

Nortier J, Baudoux T, Bunel V, Jadot I, Antoine M, Roumeguere T, Broeders N, Vanherweghem J.L.

Toxicologie Analytique et Clinique 2018, 30 (3): 167.

58. Belgian consensus statement on the diagnosis and management of patients with atypical hemolytic uremic syndrome.

Claes K.J, Massart A, Collard L, Weekers L, Goffin E, Pochet J-M, Dahan K, Morelle J, Adams B, Broeders N et al.

Acta Clinica Belgica 2018, 73 (1): 80-89.

59. Efficacy and Safety of a Tofacitinib-based Immunosuppressive Regimen After Kidney Transplantation: Results From a Long-term Extension Trial.

Busque, Stephan, MD, MSc.; Vincenti, Flavio G., MD; Tedesco Silva, Helio, MD; O’Connell, Philip J., MD; Yoshida, Atsushi, MD; Friedewald, John J., MD; Steinberg, Steven M., MD; Budde, Klemens, MD; Broeders, Emine N.,MD; Kim, Yon Su, MD;Hahn, Carolyn M., BA; Li, Huihua, MS; Chan, Gary, PharmD.

Transplantation Direct: September 2018 – Volume 4 – Issue 9 – p e380.

Liste partielle avec citations:

https://scholar.google.be/citations?user=9ZFeFBoAAAAJ&hl=fr